Apricell is an expert in spheroid formation, microenvironment testing and drug testing.
Apricell Biotechnology is a company that aims to lower the attrition rate of new drugs in clinical trials.
They are specialized in spheroid formation, microenvironment testing and drug testing and is known for their 3-in-1 Plate, a convenient hydrogel insert that enables spheroid formation, extracellular matrix integration, and drug testing in a single platform. This technology simplifies complex models and drug screening, making it an ideal solution for drug screening. The 3-in-1 Plate is compatible with various assays such as immunohistochemistry and can be imaged using standard laboratory imaging equipment.
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The 3-in-1 Plate is a hydrogel insert that fits within each well of a six-well plate
It combines spheroid/organoid formation, extracellular matrix (ECM) integration, and drug testing all in one platform
Ideal for researchers looking to embed spheroids in an ECM or conduct drug screening on complex models
Eliminates the need for transferring models from one plate to another, ensuring disturbance-free solution exchanges
Allows in situ IHC analysis and slicing of spheroids directly within the microwells of the 3-in-1 Plate, preserving the delicate morphology of models
Provides highly uniform spheroids and perfect data consistency due to the geometry of the microwells
Requires fewer cells to form organoids, eliminating the need for passaging
Applications include coculture, invasion, drug screening, assays, and imaging
2D cell cultures have significant limitations and are not an accurate representation of in vivo tissue
3D cell culture is an increasingly popular research tool that mimics the native microenvironment from which cells originated and provides more accurate gene expression profiles
The 3-in-1 Plate allows for IHC and H&E treatment directly in the platform without removing spheroids and can be embedded in paraffin and sliced without further manipulation
The platform is compatible with in-situ immunostaining and fluorescence microscopy, and spheroids can be easily dissociated on the plate for downstream cytometry analysis or used for omics analysis.
