Metatissue

provides human protein-based hydrogels, widely used in cell culture, tissue engineering, regeneration and disease modeling.

Metatissue

Cell culture has been integral to investigating basic biology before proceeding to higher organisms. However,  there is a need to first reduce and ultimately eliminate the need for animals in research. To do so there need to be reproducible human centric models available for testing that can accurately replicate the complex microenvironment of the ECM.

Metatissue provides human protein-based hydrogels, porous scaffolds and bioinks to bridge this problem. By harnessing human-derived proteins and growth factors, Metatissue eliminates the reliance on animal-derived products, thereby ensuring scientific integrity while adhering to ethical standards.

The significance of Metatissue's hydrogels extends beyond their composition. Their mechanical tunability, allowing researchers to fine-tune stiffness and crosslinking using light-based techniques, represents a paradigm shift in the field. Moreover, the practice of pooling samples to minimize lot-to-lot variability underscores Metatissue's commitment to reproducibility and reliability in research outcomes.

Customizability is another hallmark of Metatissue's offerings. Whether researchers require donor-specific formulations, enrichment or depletion of specific molecules, or different formats such as porous scaffolds, bio-inks, or hydrogels, Metatissue stands ready to meet diverse research needs.

The applications of Metatissue's hydrogels are as diverse as the challenges they address. From 3D cell culture to tissue engineering, from disease modeling for drug discovery to cancer research, these hydrogels serve as versatile platforms fostering innovation and discovery. They enable the creation of realistic tumor-like environments, facilitate stem cell proliferation, drive tissue morphogenesis, and maintain tissue homeostasis.

By enhancing the accuracy of in vitro preclinical studies, they have the potential to reduce drug development costs and accelerate time to market, thereby bringing life-saving treatments to patients more swiftly. Moreover, by adhering to the principles of the 3R's (Replacement, Reduction, Refinement), Metatissue advocates for the ethical implementation of research practices, advocating for the welfare of animals involved in scientific endeavors.

Overview of our products for Metatissue.

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0,2 % Gelatin Solution - (Pelobiotech) Cell Culture Tools
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0,2 % Gelatin Solution - (Pelobiotech) Cell Culture Tools
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0.155 M NaCl - (Cellapplications) Cell Culture Tools
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0.155 M NaCl - (Cellapplications) Cell Culture Tools
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1xPBS - (Cyagen) Cell Culture Tools
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ABLE 100 mL Disposable Bioreactor (4 units) - (ReproCell) Cell Culture Tools
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ABLE 30mL Disposable Bioreactor (6 units) - (ReproCell) Cell Culture Tools
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ABLE 500 mL Disposable Bioreactor (1 units) - (ReproCell) Cell Culture Tools
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ABLE 5mL Disposable Bioreactor (6 units) - (ReproCell) Cell Culture Tools
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ABLE Bioreactor Magnetic Stir System Base 30 mL and 100 mL (1 unit) - (ReproCell) Cell Culture Tools
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ABLE Bioreactor Magnetic Stir System Base 5 mL (1 unit) - (ReproCell) Cell Culture Tools
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ABLE Bioreactor Magnetic Stir System Controller and Motor - (ReproCell) Cell Culture Tools

Advanced Extracellular Matrix Solutions for Cell Culture and Tissue Engineering

Metatissue offers cutting-edge extracellular matrix (ECM) products sourced from Metatissue, designed to provide realistic and human-like microenvironments for cell culture, tissue engineering, and disease modeling. Our ECM products are mechanically tuneable, photocrosslinkable, versatile, reproducible, and personalized to meet the diverse needs of your research.

Why Choose Metatissue ECM Products?

  • Mechanically Tuneable: Our ECM products can be mechanically adjusted to mimic the stiffness and elasticity of various tissues, providing a more accurate in vitro environment.
  • Photocrosslinkable: Easily form hydrogels upon light exposure, allowing for precise control over the 3D structure and properties of the ECM.
  • Versatile: Suitable for a wide range of applications, including cell culture, tissue engineering, and disease modeling.
  • Reproducible: Consistent quality and performance across batches, ensuring reliable and reproducible results.
  • Personalized: Customizable to meet the specific requirements of your research projects.

Product Features

  • Ethically Sourced Human Proteins: Our ECM products are derived from ethically and readily available human sources, ensuring high biocompatibility and relevance to human biology.
  • Robust and Easy to Handle: Chemically modified to create robust materials that are easy to handle and manipulate in the lab.
  • Enhanced Cell Interactions: Designed to improve cell-to-cell and cell-to-matrix interactions, increasing the accuracy of in vitro studies.

Applications

  • Cell Culture: Provides a realistic microenvironment for cell growth and differentiation.
  • Tissue Engineering: Supports the development and regeneration of tissues in vitro.
  • Disease Modeling: Enables the creation of more accurate disease models for research and drug testing.

Benefits

  • Improved Research Accuracy: Mimics the extracellular matrix of living tissues, enhancing the correlation between laboratory research and clinical trials.
  • Reduction in Animal Testing: Provides a viable alternative to animal models, reducing the need for animal testing.
  • Accelerated Scientific Discoveries: Increases the speed of scientific discoveries by providing more accurate and reliable in vitro models.

Frequently Asked Questions

What are the main applications of Metatissue ECM products?

  • Our ECM products are used in cell culture, tissue engineering, and disease modeling to provide realistic and human-like microenvironments.

How are Metatissue ECM products different from other ECM products?

  • Our ECM products are mechanically tuneable, photocrosslinkable, versatile, reproducible, and personalized, offering superior performance and customization options.

We are here for you.

Call us, write to us or make an appointment for a personal conversation
with us on site. Please do not hesitate to call, we love to be at
your service anytime.

PELOBIOTECH GmbH
Behringstrasse 10
82152 Germany

Phone +49 (0) 89 517 286 59 0
Mail info@pelobiotech.com

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