Ellis Bio

Ellis Bio PELOBiotech GmbH

Ellis Bio are experts in DNA methylation

Ellis Bio is specializing in innovative solutions for DNA methylation analysis, offering superior bisulfite conversion kits that set new standards in low-input methylation detection. Advanced Bisulfite Conversion Technologies

Filter products

There are no entries on the watch list.

Ellis Bio provides two bisulfite conversion product lines designed to deliver gentle yet highly efficient DNA methylation analysis.

SuperMethyl Fast: The fastest bisulfite conversion method available, completing C-to-U conversion in just 35 minutes. This ultra-mild, high-efficiency approach minimizes DNA degradation and false positives while supporting very low DNA inputs, including cfDNA, FFPE-derived DNA, and forensic trace samples.

SuperMethyl Max: Featuring ultra-mild bisulfite conversion chemistry that surpasses enzyme-based methods, SuperMethyl Max excels in recovering high-quality DNA libraries with longer insert sizes and superior accuracy. It supports ultra-low input samples down to 100pg and is well-suited for challenging samples such as single cells, ancient DNA, and liquid biopsies.

Why Choose Ellis Bio?

  • Speed and sensitivity: SuperMethyl Fast accelerates your workflow with up to 10x faster conversion times compared to traditional methods without compromising accuracy.
  • High DNA integrity and yield: Both product lines maintain DNA integrity by using ultra-mild reaction conditions, ensuring optimal downstream analysis.Broad Application Spectrum: Perfect for methylation studies in cancer research, epigenetics, single-cell analysis, forensic biology, and more.
  • Ease of use: Ready-to-use reagents and simplified protocols enable rapid integration into your lab workflow.

Super Methyl Max

Advanced Bisulfite Conversion Technologies

Fast & simple: Total protocol time of approximately 2 - 3 hours with minimal hands-on steps

Exceptional C-to-T conversion efficiency: Greater than 99.5% conversion rates

Low degradation: Optimized chemistry supports efficient bisulfite conversion while preserving DNA quality

Low-input compatible: Validated for 100 pg to 50 ng of cell-free DNA (cfDNA), genomic DNA (gDNA), or FFPE derived DNA

Low background noise: Reduces false positives and enhances signal clarity

Uniform GC coverage: Delivers consistent coverage across GC-rich and GC-poor regions

Enhanced CpG detection: Detects more CpG sites with fewer sequencing reads

High library complexity: Produces libraries with greater complexity and larger insert sizes compared to conventional bisulfite conversion

Super Methyl Fast

The company provides also an advanced FAST kit:

35 minutes total workflow

High efficiency:  Consistently delivers over 99.5% conversion of unmethylated cytosines, ensuring accurate analysis while preserving methylated cytosines

Improved data accuracy: shorter methylation time results in fewer false positives

Beads or colon-based

Be surprised by the cost-competitive price

Versatile applications: Ideal for a variety of applications including PCR, methylation-specific PCR (MSP), arrays, library preps, and next-generation sequencing (NGS)