Posts tagged “ ips”

  • Ever wondered what an animal-source free Extracellular Matrix (ECM) could do to your Pluripotent Stem Cells (PSC)?Our partner denovoMATRIX has developed a chemically defined, animal and human component-free coating that recapitulates the function of the #ECM by combining glycosaminoglycans with biofunctional peptides, called myMATRIX iPSC. This matrix shows great single-cell attachment as well as robust […]

    PELONews: myMATRIX iPSC: Xeno-free & Chemically Defined iPSC Culture

    Ever wondered what an animal-source free Extracellular Matrix (ECM) could do to your Pluripotent Stem Cells (PSC)?Our partner denovoMATRIX has developed a chemically defined, animal and human component-free coating that recapitulates the function of the #ECM by combining glycosaminoglycans with biofunctional peptides, called myMATRIX iPSC. This matrix shows great single-cell attachment as well as robust and reliable growth in long-term culture. Importantly, PSCs grown on #myMATRIX iPSC retain their...
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  • PELOBiotech welcomes a new partner aboard: As of today we happily offer HumaTein products from Rokit Healthcare (South Korea) in Europe. Cell Culture Expert PELObiotech widens its extensive portfolio of specific matrices. HumaTein™ composition is optimized for a target cell type growth and proliferation in a native-like environment. The best possible Extracellular Matrix (ECM) is […]

    PELONews: New Partner Rokit Healthcare for Human Native-like Coating and Targeted Cell type Growth

    PELOBiotech welcomes a new partner aboard: As of today we happily offer HumaTein products from Rokit Healthcare (South Korea) in Europe. Cell Culture Expert PELObiotech widens its extensive portfolio of specific matrices. HumaTein™ composition is optimized for a target cell type growth and proliferation in a native-like environment. The best possible Extracellular Matrix (ECM) is most important for  cell attachment, proliferation and migration, and plays an import role as a growth factor...
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  • A new combination of chemical compounds could lead the way to more cost-effective stem cell culture Human pluripotent stem cells (hPSCs) can infinitely self-renew and develop into all major cell types in the body, making them important for organ repair and replacement. But culturing them in large quantities can be expensive. Now, scientists at Japan’s […]

    Kyoto University Found Way of Culturing Stem Cells More Cost-Effective

    A new combination of chemical compounds could lead the way to more cost-effective stem cell culture Human pluripotent stem cells (hPSCs) can infinitely self-renew and develop into all major cell types in the body, making them important for organ repair and replacement. But culturing them in large quantities can be expensive. Now, scientists at Japan's Kyoto University, with colleagues in India and Iran, have developed a more cost-effective culture by using a new combination of chemical compounds. Current...
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  • A primitive role for ATF6 The endoplasmic reticulum (ER) mediates and monitors the folding, packaging, and transport of proteins in cells. The unfolded protein response (UPR) preserves ER homeostasis in the adult organism; however, inactivating mutations in the UPR-associated transcription factor ATF6 cause congenital vision defects, suggesting an embryonic role as well. Kroeger et al. […]

    The Unfolded Protein Response Regulator ATF6 promotes Mesodermal Differentiation

    A primitive role for ATF6 The endoplasmic reticulum (ER) mediates and monitors the folding, packaging, and transport of proteins in cells. The unfolded protein response (UPR) preserves ER homeostasis in the adult organism; however, inactivating mutations in the UPR-associated transcription factor ATF6 cause congenital vision defects, suggesting an embryonic role as well. Kroeger et al. found that ATF6 was critical to the differentiation of stem cells to the mesodermal lineage, at least in part,...
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  • Kyoto University said a researcher at its iPS institute headed by Nobel Prize winner Shinya Yamanaka has engaged in “falsification and fabrication” in a paper published last year in scientific journal Stem Cell Reports. “I am very regretful for not being able to prevent the dishonesty,” said Yamanaka, professor at Kyoto University who won the […]

    Researcher at Kyoto Univ.’s iPS institute falsifies data for paper

    Kyoto University said a researcher at its iPS institute headed by Nobel Prize winner Shinya Yamanaka has engaged in "falsification and fabrication" in a paper published last year in scientific journal Stem Cell Reports. "I am very regretful for not being able to prevent the dishonesty," said Yamanaka, professor at Kyoto University who won the Nobel Prize in medicine in 2012 for discovering induced pluripotent stem cells, or iPS cells. "I will take (the incident) seriously and provide education...
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  • Scientists in Australia have used a 3D printer to create nerve cells found in the brain using a special bio-ink made from stem cells. The research takes us a step closer to making replacement brain tissue derived from a patient’s own skin or blood cells to help treat conditions such as brain injury, Parkinson’s disease, […]

    3D-printed brain-like tissue from SC

    Scientists in Australia have used a 3D printer to create nerve cells found in the brain using a special bio-ink made from stem cells. The research takes us a step closer to making replacement brain tissue derived from a patient’s own skin or blood cells to help treat conditions such as brain injury, Parkinson’s disease, epilepsy and schizophrenia. The bio-ink is made of human induced pluripotent stem cells (#iPSC), which have the same power as embryonic stem cells to turn into any cell...
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  • This is the stuff from which the cartilage was grown: induced pluripotent stem cells, often called #iPS cells. Guiding a recent tour of a Kyoto University lab, a staff member holds up a transparent container. Inside are tiny pale spheres, no bigger than peas, floating in a clear liquid. “This is cartilage,” explains the guide, […]

    Waiting to Reprogram Your Cells? Don’t Hold Your Breath

    This is the stuff from which the cartilage was grown: induced pluripotent stem cells, often called #iPS cells. Guiding a recent tour of a Kyoto University lab, a staff member holds up a transparent container. Inside are tiny pale spheres, no bigger than peas, floating in a clear liquid. “This is cartilage,” explains the guide, Hiroyuki Wadahama. “It was made here from human iPS cells.” A monitor attached to a nearby microscope shows a mass of pink and purple dots. This is the stuff from...
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  • Gut Tissue with Functional Nervous System Created in Laboratory for First Time

    Scientists created human gut tissue containing a functional nervous system in the laboratory for the first time. According to the authors of the study, “Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system,” which was published in the leading scientific journal Nature Medicine, this research could help treat people with conditions such as inflammatory bowel disease (IBD). However, they warned: “The complexity of the [gut] tissue will...
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