No Matrigel at hand? Our new partner Tissue Click offers PhenoDrive which has a multifunctional nature.
Unlike GelMatrix/Matrigel it can be used as a coating, in suspension or as a bio-ink. This offers a simple and effective scale-up reducing experimental optimization and its time cost.
Valeria Perugini et al. have already published a paper in 2022. -> https://doi.org/10.1007/s10856-022-06658-3
Development of Scaffold-free vascularized pancreatic beta-islets in vitro models by the anchoring of cell lines to a biologand –functionalized gelatine substrate. V
Abstract:
The formation of bioengineered pancreatic islets through cell anchoring to a gelatine-based biomaterial, PhenoDrive-Y, is able to mimic the basement membrane of tissues. PhenoDrive-Y led human pancreatic ß Cell line and human umbilical endothelial cell lines structure which is similar to natural vascularized pancreatic islets. The study shows the potential of PhenoDrive-Y as a substrate for the development of bioengineered vascularized pancreatic islets making it suitable for new therapeutics.
Phenodrive vs GelMatrix/Matrigel at a glance.