New clues to Myelination could help Identify ways to Intervene in Neurodegenerative Diseases

“If we can further enhance our understanding of how these oligodendrocyte precursor cells mature, then it may be possible to stimulate them to replace myelin in diseases like multiple sclerosis.”, says Pablo Paez, PhD, Assistant professor and research scientist , unters James Kelly Research Institute at University at Buffalo, US.

 The Researchers at the University at Buffalo have identified a critical step in myelination after birth that has significance for treating neurodegenerative diseases like multiple sclerosis, in which myelin is lost or damaged. Myelin is the protective coating that neurons need to function. The preclinical research  concerns oligodendrocytes, the cells that make myelin, and the progenitor cells that are their precursors. The work involved the study of voltage-operated calcium channels, which are responsible for initiating many physiological functions.