Hidden Immune Cells play Key Role

Northwestern Medicine scientists have discovered that a subset of immune cells called nonclassical monocytes (#NCMs), previously unknown to reside in the lungs, play a key role in driving , primary graft dysfunction (PGD), the leading cause of death after lung #transplantation.

The study, published in Science Translational Medicine, also demonstrates targeting these cells could lead to novel treatments for PGD, a complication that currently impacts more than half of transplant patients.
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