A Cedars-Sinai study has revealed that a research team at the Cedars-Sinai Board of Governors Regenerative Medicine Institute has discovered a new technique that has the potential to treat inherited diseases by removing genetic defects has been shown for the first time to hinder retinal degeneration in rats with a type of inherited blindness.
The focus of the researchers was on inherited retinitis pigmentosa – a degenerative eye disease with no known cure that can lead to blindness. Â A technique called CRISPR/Cas9 was used by the researchers to remove a genetic mutation that causes the blindness disease.
The technique CRISPR/Cas9 (CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, the type of DNA sequences involved in this process) is adapted from a strategy used by bacteria to fight invading viruses. The study was carried out in mice, however the finding are significant as they have potential implication sin humans as well. The details of the study findings were published recently in the journal Molecular Therapy.
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