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High quality human platelet lysate (hPL) in GMP and research quality!

hPL (human platelet lysate) is used for MSC expansion, Exosome production using MSC and as replacement for FBS) in research and clinical application.

 

Our partner AventaCell produces hPL in different qualities from expired platelets:

  • UltraGro
  • UltraGro advanced
  • UltraGro Pure
  • UltraGro advanced GI
  • UltraGro PURE GI
  • Exosome-Depleted UltraGRO™-PURE GI Research grade

Human Platelet Lysate (HPL) by AventaCell Biomedical

Premium Human Platelet Lysate for Advanced Cell Culture and Tissue Regeneration

Cellovations offers high-quality human platelet lysate (HPL) products, sourced from AventaCell BioMedical Corp, to support your cell culture and tissue regeneration research. Our HPL products are designed to provide a serum-free alternative for cell expansion and production, ensuring safety, efficiency, and cost-effectiveness.

Why Choose Cellovations HPL?

  • Animal Serum-Free: Our HPL products eliminate the need for animal serum, reducing the risk of contamination and improving the safety of your research.
  • High Compliance and Scalability: Designed to meet the highest standards of compliance, our HPL products are scalable to support both small and large-scale research projects.
  • Cost-Effective: Our HPL products offer a cost-effective solution for cell culture and tissue regeneration, without compromising on quality.

Frequently Asked Questions

What is human platelet lysate (HPL)?

  • HPL is a serum-free supplement derived from human platelets, rich in growth factors and cytokines, used to promote cell growth and proliferation in cell culture.

How is Cellovations HPL different from other serum-free supplements?

  • Our HPL is sourced from AventaCell BioMedical Corp, ensuring high quality and consistency. It is specifically designed to support a wide range of cell types and applications, providing a reliable alternative to animal serum.
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Product Features

  • Derived from  expired Human Platelets: Our HPL is derived from expired human platelets, providing a rich source of growth factors and cytokines essential for cell proliferation and differentiation.
  • Enhanced Cell Growth: Promotes the expansion and production of a broad range of cells, including mesenchymal stem cells and multiple immunocell lines.
  • Batch Consistency: Each batch of HPL is rigorously tested to ensure consistency and reliability in your research.

Applications

  • Cell Therapy: Ideal for expanding and producing cells for therapeutic applications.
  • Regenerative Medicine: Supports tissue regeneration and repair in various research and clinical settings.
  • Translational Research: Facilitates the development of cell and tissue-based therapies.

Benefits

  • Safety and Efficacy: Our HPL products are designed to accelerate the research, development, and commercialization of safe and effective cell and tissue-based therapeutics.
  • Versatility: Suitable for a wide range of cell types and research applications, providing flexibility in your experimental design.
  • Quality Assurance: Each batch undergoes stringent quality control to ensure high performance and reproducibility.
More Details

hPLMA

PHOTOPOLYMERIZABLE HYDROGEL derived from human platelet layset

hPLMA PHOTOPOLYMERIZABLE HYDROGEL from our partner Metatissue. This is our next step towards reducing the need for animals in research and making human-centric models available to accurately replicate the complex microenvironment of the extracellular matrix.

 

hPLMA PHOTOPOLYMERIZABLE HYDROGEL is a xeno-free, animal serum-free, bioactive platelet lysates-based platform that provides physiologically relevant microenvironments for cells cultured in vitro. It is composed of several proteins, including growth factors and cytokines. These bio-active proteins are known to be key components involved in cell adhesion and proliferation processes.

 

hPLMA is manufactured from platelet units obtained from screened healthy donors designated for therapeutic transfusion. Each donor undergoes testing, and non-reactivity is
confirmed for HBsAg, anti-HBc, anti-HIV-1/2, anti-HCV, anti-HTLV-1/2, anti-T. cruzi, HIV-1, HCV, HBV, WNV nucleic acid testing, and syphilis micro hemagglutination assay.

hPLMA is chemically modified with photoresponsive groups to polymerize only when exposed to ultraviolet (UV) or visible light. Therefore, a photoinitiator is required to initiate the polymerization process.

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Main Components

  • Serum Albumin
  • EGF Epidermal growth factor
  • PDGF Platelet-derived growth factor
  • Fibrinogen
  • VEGF Vascular endothelial growth factor
  • Complement 3
  • Serotransferrin

Realistic Tumor-like Environments

ExtraGel Matrix

  • Extracellular Matrix Hydrogel
  • Extracellular Matrix Hydrogel, high concentration
  • Extracellular Matrix Hydrogel, reduced growth factor
  • Extracellular Matrix Hydrogel, hESC qualified
  • Extracellular Matrix Hydrogel, high concentration, reduced growth factor

Also available phenol-red-free.

Typical protein concentrations for Extragel Matrix by our partner MegaRobo range between 8 to 12 mg/mL. Extragel Matrix High Concentration ranges from 18 to 22 mg/mL. In some instances, individual lots may fall outside this range. A lot-specific Certificate of Analysis is provided with each. Each lot of Extragel Matrix documents exact endotoxin and protein concentrations.

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Key features

Extragel is suitable for Advanced 2D, 3D, and in vivo applications e.g. angiogenesis, stem cell maintenance and differentiation, tumor formations and more.

  • High safety: Tested negative for LDEV, fungi, bacteria, and mycoplasma, conveniently used in the lab without involving pollutants.
  • Lot-to-lot consistent: Strict quality inspection to ensure product stability, consistency, and reliability in performance between different batches.
  • Compatible: Compatible with many kinds of cell culture media
  • Ample Productive:  Product yield reaches 1L volume in one single batch manufacture to assure sufficient supply.

Each Lot would be conformed by:

  • Protein concentration: more/equal than/to 8 mg/mL
  • Gelation within 30 minutes at 37 °C
  • Functional validation of neurite outgrowth and organoid growth
  • Fungi, Bacteria, and Mycoplasma-free
  • LDEV-free Endotoxin less than/equal to 4 EU/mL

->Go to our catalog to learn more.

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