Archive for Category: General

Showing 101 – 110 of 113 results

  • New drug screening tool reduces need for animal testing

    Because their job is to eliminate drugs and other foreign compounds from the body, the kidneys are a main target for any toxic effects. Now, after finding an effective way of producing human kidney cells from stem cells, a team of scientists has developed the first animal-free screening platform that is capable of accurately predicting the toxic effects of compounds on the kidney. To read more please click here.
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  • Global Regenerative Medicine Industry 2015 Status

    The Global Regenerative Medicine Industry 2015 Market Research Report is a professional and in-depth study on the current state of the Regenerative Medicine industry. The report provides a basic overview of the industry including definitions, classifications, applications and industry chain structure.The Regenerative Medicine market analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status. View Full Report...
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  • Biomarkers of severe dengue disease

    Dengue virus infection presents a wide spectrum of manifestations including asymptomatic condition, dengue fever (DF), or severe forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) in affected individuals. The early prediction of severe dengue in patients without any warning signs who may later develop severe DHF is very important to choose appropriate intensive supportive therapy since available vaccines for immunization are yet to be approved. To read this review please...
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  • Researchers develop first animal-free screening platforms to predict toxic kidney injury

    Researchers from the Institute of Bioengineering and Nanotechnology (IBN) have developed the first animal-free screening platforms capable of predicting the toxic effects of compounds on the human kidney accurately. Their latest technological advancement involves the use of human induced pluripotent stem cells (iPSCs) in their renal screening platform (Kandasamy et al., 2015). To realize this breakthrough, the scientists have developed an effective way of producing human renal cells from iPSCs, and...
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  • A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging

    An ongoing challenge in biomedical research is the search for simple, yet robust assays using 3D cell cultures for toxicity screening. This study addresses that challenge with a novel spheroid assay, wherein spheroids, formed by magnetic 3D bioprinting, contract immediately as cells rearrange and compact the spheroid in relation to viability and cytoskeletal organization. Thus, spheroid size can be used as a simple metric for toxicity. The goal of this study was to validate spheroid contraction as...
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  • New Method for Testing IPS Cells Differentiation Potential Could Lead to More Potent Treatments

    Though the discovery of Induced Pluripotent Stem Cells (iPSCs) has great potential to help in the development of regenerative medicine therapies, the attempts to discover how safe and potent use of iPSCs are in treatment of diseases has been inconclusive or contradictory. Atlas Regeneration Inc., working together with Insilico Medicine, has developed a method for using pathway activity analysis to test for differentiation potential that makes iPSCs effective much more quickly than was previously...
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  • Is company’s claim of meat without murder too good to be true?

    Meat without murder, or “animal” flesh grown in a lab for human consumption, has been touted as an ethical gourmand’s dream for nearly a century, but is it a fantasy too good to be true? Not according to Modern Meadow, a Brooklyn biotech startup that is promising to bring so-called in vitro meat to a dinner table near you, although it is not without its critics. To read more go to The Guardian
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  • Informed consent for medical reseach

    This article written by Leslie Jacqueline Greenberg (Professor of Human Genetics: Stem Cell Researcher at University of Cape Town) shows how important a informed consent is for medical research. She claims that is neccessary to have different informed consents for different stem cells. Click here to read more
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  • New polymer reduces ice crystal formation during cryopreservation

    Preventing ice crystal formation is one of the main goals when developing new cryopreservation techniques. Ice crystals cause direct injury to the cells during the freezing and particularly thawing process. The ice is also the main culprit for secondary freezing damage that involves the solutes used in the cryoprotectant solution. To read more please click here.
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  • Chemical Cocktails Produce Neurons

    Over the past several years, scientists have been in hot pursuit of finding an efficient way to directly transform skin cells to brain cells—skipping an intermediate pluripotent step. Genetic approaches have worked to varying degrees. Now, two independent groups report having made the process even simpler, by soaking fibroblasts in combinations of small molecules, thereby obviating the need to tinker with gene expression to turn the cells into neurons. To read more please click here.
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