3D Tissue Culture Model Mimics Gut Infections

With threats like zika, ebola, #SARS and tuberculosis increasing, researchers are using predictive tissue culture models to more accurately reflect how humans respond to pathogens.

The lack of sophisticated models has greatly slowed the ability to understand infectious disease from both the host and the pathogen perspective.

One approach to address this problem is the use of predictive tissue culture models. To develop these models, an understanding of how cells and tissues in our bodies function in a #3D context is required.

A research team from the Arizona State University Biodesign Institute team and NASA’s Johnson Space Center, have developed a realistic 3D co-culture model, which incorporates an important immune defense cell type found in the intestine, macrophages, key cells targeted by salmonella, a leading cause of food poisoning and systemic disease worldwide.

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