PELONews: Talk about Native Organotypic ECM Great Success

To a talk about applied 3D cell culture PELOBiotech GmbH and its US partner EastRiver BioSolutions from New York invited to Sky-Room at the IZB end of November 2018. Around 30 scientists from Munich biotech companies, LMU, Klinikum rechts der Isar, Helmholtz Centre and Hochschule Munich discussed with John O´Neill, CSO EastRiver, the importance of the right physiological environment for cell growth. Guests came from Switzerland and the University of Dublin, Ireland, Prof. Günther Eisner, too.

In his lecture on Native Organotypic ECM (Extracellular Matrix) for Coatings, Hydrogels and Scaffolds John made it very clear how the targeted use of native coatings not only proliferates the cells but also improves the adhesion of the cells. “You have to imagine if your cells are in a room with only brick walls. It’s not very comfortable, is it?”, John O´Neill explains the functionality of his organspecific product line compared to competitors such as Matrigel. Those offer often a cocktail disease-associated physiological factors such as collagens. This convinced the scientists: “The future of today’s research is clearly moving in the direction of 3D,” says one of the talk participants. “The right environment for the cells is becoming increasingly important in my field,” she says. Possible applications include stem cells, tissue engineering, 3D cell culture and cancer research.

Another participant hopes to receive support for his drug screening project from the novel organoid ECMs: “International research on pancreas organoid models is still in its infancy anyway.”

CSO John O´Neill also had a delicacy for his audience: “Very soon we will be able to offer ECMs not only of animated but also of human origin”. His colleagues Richard Nguyen, Business Development, and EastRiver Board Member Anthony A. Curro were particularly impressed by the IZB: “The event was a great success for us,” said Anthony A. Curro , who is also CEO  the Biotech-company Immplacate: “It’s like old times in New York, Alexandria Biotech Center. The audience, a great campus, great people, great atmosphere.” They will be back – soon, and then EastRiver will have a new name: XYLYX.

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